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Mechanistic insight into the nucleus–vacuole junction based on the Vac8p–Nvj1p crystal structure

Formation of the nucleus–vacuole junction (NVJ) is mediated by direct interaction between the vacuolar protein Vac8p and the outer nuclear endoplasmic reticulum membrane protein Nvj1p. Herein we report the crystal structure of Vac8p bound to Nvj1p at 2.4-Å resolution. Vac8p comprises a flexibly conn...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Jeong, Hanbin, Park, Jumi, Kim, Hye-In, Lee, Miriam, Ko, Young-Joon, Lee, Sanghwa, Jun, Youngsoo, Lee, Changwook
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468681/
https://ncbi.nlm.nih.gov/pubmed/28533415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701030114
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