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Mechanistic insight into the nucleus–vacuole junction based on the Vac8p–Nvj1p crystal structure

Formation of the nucleus–vacuole junction (NVJ) is mediated by direct interaction between the vacuolar protein Vac8p and the outer nuclear endoplasmic reticulum membrane protein Nvj1p. Herein we report the crystal structure of Vac8p bound to Nvj1p at 2.4-Å resolution. Vac8p comprises a flexibly conn...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Jeong, Hanbin, Park, Jumi, Kim, Hye-In, Lee, Miriam, Ko, Young-Joon, Lee, Sanghwa, Jun, Youngsoo, Lee, Changwook
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468681/
https://ncbi.nlm.nih.gov/pubmed/28533415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1701030114
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