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Histone-binding of DPF2 mediates its repressive role in myeloid differentiation

Double plant homeodomain finger 2 (DPF2) is a highly evolutionarily conserved member of the d4 protein family that is ubiquitously expressed in human tissues and was recently shown to inhibit the myeloid differentiation of hematopoietic stem/progenitor and acute myelogenous leukemia cells. Here, we...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Huber, Ferdinand M., Greenblatt, Sarah M., Davenport, Andrew M., Martinez, Concepcion, Xu, Ye, Vu, Ly P., Nimer, Stephen D., Hoelz, André
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468650/
https://ncbi.nlm.nih.gov/pubmed/28533407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1700328114
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