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Reconstructing blood stem cell regulatory network models from single-cell molecular profiles

Adult blood contains a mixture of mature cell types, each with specialized functions. Single hematopoietic stem cells (HSCs) have been functionally shown to generate all mature cell types for the lifetime of the organism. Differentiation of HSCs toward alternative lineages must be balanced at the po...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Hamey, Fiona K., Nestorowa, Sonia, Kinston, Sarah J., Kent, David G., Wilson, Nicola K., Göttgens, Berthold
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468644/
https://ncbi.nlm.nih.gov/pubmed/28584094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1610609114
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