Sarcomas with CIC-rearrangements are a distinct pathologic entity with aggressive outcome: A clinicopathologic and molecular study of 115 cases

CIC-DUX4 gene fusion, resulting from either a t(4;19) or t(10;19) translocation, is the most common genetic abnormality detected in EWSR1-negative small blue round cell tumors (SBRCTs). Following their discovery it was debated if these tumors should be classified as variants of Ewing sarcoma (i.e. a...

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Pubblicato in:Am J Surg Pathol
Autori principali: Antonescu, Cristina R., Owosho, Adepitan A., Zhang, Lei, Chen, Sonja, Deniz, Kemal, Huryn, Joseph M., Kao, Yu-Chien, Huang, Shih-Chiang, Singer, Samuel, Tap, William, Schaefer, Inga-Marie, Fletcher, Christopher D
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468475/
https://ncbi.nlm.nih.gov/pubmed/28346326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAS.0000000000000846
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