Cardioprotective Effects of SIRT6 in a Mouse Model of Transverse Aortic Constriction-Induced Heart Failure

SIRT6, a member of the NAD (+)-dependent class III deacetylase sirtuin family, plays important roles in the maintenance of cardiovascular homeostasis. Telomere shortening is a risk factor for age-associated diseases, including heart disease. In the present study, we investigated the role of SIRT6 an...

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Vydáno v:Front Physiol
Hlavní autoři: Li, Yongming, Meng, Xianda, Wang, Wenguang, Liu, Fu, Hao, Zhiru, Yang, Yang, Zhao, Jinbo, Yin, Wensi, Xu, Lijuan, Zhao, Ruiping, Hu, Jiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Physiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468374/
https://ncbi.nlm.nih.gov/pubmed/28659816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.00394
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