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An Advanced Deep Learning Approach for Ki-67 Stained Hotspot Detection and Proliferation Rate Scoring for Prognostic Evaluation of Breast Cancer

Being a non-histone protein, Ki-67 is one of the essential biomarkers for the immunohistochemical assessment of proliferation rate in breast cancer screening and grading. The Ki-67 signature is always sensitive to radiotherapy and chemotherapy. Due to random morphological, color and intensity variat...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Saha, Monjoy, Chakraborty, Chandan, Arun, Indu, Ahmed, Rosina, Chatterjee, Sanjoy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5468356/
https://ncbi.nlm.nih.gov/pubmed/28607456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03405-5
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