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IGF-1 mediated Neurogenesis Involves a Novel RIT1/Akt/Sox2 Cascade
Insulin-like growth factor 1 (IGF-1) is known to have diverse effects on brain structure and function, including the promotion of stem cell proliferation and neurogenesis in the adult dentate gyrus. However, the intracellular pathways downstream of the IGF-1 receptor that contribute to these diverse...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5468318/ https://ncbi.nlm.nih.gov/pubmed/28607354 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03641-9 |
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