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Quantification of within-sample genetic heterogeneity from SNP-array data
Intra-tumour genetic heterogeneity (ITH) fosters drug resistance and is a critical hurdle to clinical treatment. ITH can be well-measured using multi-region sampling but this is costly and challenging to implement. There is therefore a need for tools to estimate ITH in individual samples, using stan...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5468233/ https://ncbi.nlm.nih.gov/pubmed/28607403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03496-0 |
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