Selective activation of anti-CD73 mechanisms in control of primary tumors and metastases

The emerging role for CD73 in driving cancer growth and metastasis has presented opportunities to develop anti-CD73 monoclonal antibodies (mAbs) in the treatment of human cancers. Blockade of CD73 by antagonistic CD73 mAbs ameliorates tumor growth and metastasis via the inhibition of enzymatic and n...

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發表在:Oncoimmunology
Main Authors: Vijayan, Dipti, Barkauskas, Deborah S., Stannard, Kimberley, Sult, Erin, Buonpane, Rebecca, Takeda, Kazuyoshi, Teng, Michele W. L., Sachsenmeier, Kris, Hay, Carl, Smyth, Mark J.
格式: Artigo
語言:Inglês
出版: Taylor & Francis 2017
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467999/
https://ncbi.nlm.nih.gov/pubmed/28638737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1312044
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