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Long-term efficacy and safety of nalfurafine hydrochloride on pruritus in chronic liver disease patients: Patient-reported outcome based analyses

BACKGROUND AND AIM: Among various symptoms accompanied with chronic liver disease, pruritus affects the quality of life of patients, causing physical and mental stress, and worsens hepatic function. Recently, κ-opioid receptor agonist, nalfurafine hydrochloride was approved to treat central pruritus...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Kamimura, Kenya, Yokoo, Takeshi, Kamimura, Hiroteru, Sakamaki, Akira, Abe, Satoshi, Tsuchiya, Atsunori, Takamura, Masaaki, Kawai, Hirokazu, Yamagiwa, Satoshi, Terai, Shuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467861/
https://ncbi.nlm.nih.gov/pubmed/28604788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178991
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