Potential therapeutic impact of CD13 expression in non-small cell lung cancer

BACKGROUND: Aminopeptidase N (CD13) is a zinc-binding protease that has functional effects on both cancerogenesis and tumor angiogenesis. Since CD13 is an antigen suitable for molecular targeted therapies (e.g. tTF-NGR induced tumor vascular infarction), we evaluated its impact in NSCLC patients, an...

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Publicado en:PLoS One
Main Authors: Schmidt, Lars Henning, Brand, Caroline, Stucke-Ring, Janine, Schliemann, Christoph, Kessler, Torsten, Harrach, Saliha, Mohr, Michael, Görlich, Dennis, Marra, Alessandro, Hillejan, Ludger, Müller-Tidow, Carsten, Lenz, Georg, Wardelmann, Eva, Wiewrodt, Rainer, Berdel, Wolfgang E., Schwöppe, Christian, Hartmann, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467809/
https://ncbi.nlm.nih.gov/pubmed/28604784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177146
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