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Sequential ionic and conformational signaling by calcium channels drives neuronal gene expression

Voltage-gated Ca(V)1.2 channels (L-type calcium channel α1C subunits) are critical mediators of transcription-dependent neural plasticity. Whether these channels signal via the influx of calcium ion (Ca(2+)), voltage-dependent conformational change (VΔC), or a combination of the two has thus far bee...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Li, Boxing, Tadross, Michael R., Tsien, Richard W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467645/
https://ncbi.nlm.nih.gov/pubmed/26912895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad3647
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