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Sequential ionic and conformational signaling by calcium channels drives neuronal gene expression
Voltage-gated Ca(V)1.2 channels (L-type calcium channel α1C subunits) are critical mediators of transcription-dependent neural plasticity. Whether these channels signal via the influx of calcium ion (Ca(2+)), voltage-dependent conformational change (VΔC), or a combination of the two has thus far bee...
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Publicado no: | Science |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5467645/ https://ncbi.nlm.nih.gov/pubmed/26912895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aad3647 |
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