USP22 mediates the multidrug resistance of hepatocellular carcinoma via the SIRT1/AKT/MRP1 signaling pathway

Drug treatments for hepatocellular carcinoma (HCC) often fail because of multidrug resistance (MDR). The mechanisms of MDR are complex but cancer stem cells (CSCs), which are able to self‐renew and differentiate, have recently been shown to be involved. The deubiquitinating enzyme ubiquitin‐specific...

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Dettagli Bibliografici
Pubblicato in:Mol Oncol
Autori principali: Ling, Sunbin, Li, Jie, Shan, Qiaonan, Dai, Haojiang, Lu, Di, Wen, Xue, Song, Penghong, Xie, Haiyang, Zhou, Lin, Liu, Jimin, Xu, Xiao, Zheng, Shusen
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467492/
https://ncbi.nlm.nih.gov/pubmed/28417539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12067
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