Transforming Growth Factor-β2 Downregulates Major Histocompatibility Complex (MHC) I and MHC II Surface Expression on Equine Bone Marrow-Derived Mesenchymal Stem Cells Without Altering Other Phenotypic Cell Surface Markers

Allogeneic mesenchymal stem cells (MSCs) are a promising cell source for treating musculoskeletal injuries in horses. Effective and safe allogeneic therapy may be hindered, however, by recipient immune recognition and rejection of major histocompatibility complex (MHC)-mismatched MSCs. Development o...

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Bibliographische Detailangaben
Veröffentlicht in:Front Vet Sci
Hauptverfasser: Berglund, Alix K., Fisher, Matthew B., Cameron, Kristin A., Poole, Emma J., Schnabel, Lauren V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Veterinary Science
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466990/
https://ncbi.nlm.nih.gov/pubmed/28660198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fvets.2017.00084
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