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Real-time imaging of intestinal bacterial β-glucuronidase activity by hydrolysis of a fluorescent probe
Intestinal bacterial β-glucuronidase (βG) hydrolyzes glucuronidated metabolites to their toxic form in intestines, resulting in intestinal damage. The development of a method to inhibit βG is thus important but has been limited by the difficulty of directly assessing enzyme activity in live animals....
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| Publicado no: | Sci Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5466677/ https://ncbi.nlm.nih.gov/pubmed/28600512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03252-4 |
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