Imipramine Inhibits Chikungunya Virus Replication in Human Skin Fibroblasts through Interference with Intracellular Cholesterol Trafficking

Chikungunya virus (CHIKV) is an emerging arbovirus of the Togaviridae family that poses a present worldwide threat to human in the absence of any licensed vaccine or antiviral treatment to control viral infection. Here, we show that compounds interfering with intracellular cholesterol transport have...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Wichit, Sineewanlaya, Hamel, Rodolphe, Bernard, Eric, Talignani, Loïc, Diop, Fodé, Ferraris, Pauline, Liegeois, Florian, Ekchariyawat, Peeraya, Luplertlop, Natthanej, Surasombatpattana, Pornapat, Thomas, Frédéric, Merits, Andres, Choumet, Valérie, Roques, Pierre, Yssel, Hans, Briant, Laurence, Missé, Dorothée
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466638/
https://ncbi.nlm.nih.gov/pubmed/28600536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03316-5
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