Synthesis, Chemical Characterization and Multiscale Biological Evaluation of a Dimeric-cRGD Peptide for Targeted Imaging of α(V)β(3) Integrin Activity

Cyclic peptides containing the Arg-Gly-Asp (RGD) sequence have been shown to specifically bind the angiogenesis biomarker α (V) β (3) integrin. We report the synthesis, chemical characterization, and biological evaluation of two novel dimeric cyclic RGD-based molecular probes for the targeted imagin...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Hedhli, Jamila, Czerwinski, Andrzej, Schuelke, Matthew, Płoska, Agata, Sowinski, Paweł, Hood, Lukas La, Mamer, Spencer B., Cole, John A., Czaplewska, Paulina, Banach, Maciej, Dobrucki, Iwona T., Kalinowski, Leszek, Imoukhuede, Princess, Dobrucki, Lawrence W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466598/
https://ncbi.nlm.nih.gov/pubmed/28600529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03224-8
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi