Proliferation extent of CD34(+) cells as a key parameter to maximize megakaryocytic differentiation of umbilical cord blood-derived hematopoietic stem/progenitor cells in a two-stage culture protocol()

Co-infusion of ex-vivo generated megakaryocytic progenitors with hematopoietic stem/progenitor cells (HSC/HPC) may contribute to a faster platelet recovery upon umbilical cord blood (UCB) transplantation. A two stage protocol containing cell expansion and megakaryocyte (Mk) differentiation was estab...

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Détails bibliographiques
Publié dans:Biotechnol Rep (Amst)
Auteurs principaux: Hatami, Javad, Andrade, Pedro Z., Bacalhau, Denise, Cirurgião, Fernando, Ferreira, Frederico Castelo, Cabral, Joaquim M.S., da Silva, Cláudia L.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2014
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466120/
https://ncbi.nlm.nih.gov/pubmed/28626662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.btre.2014.07.002
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