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Determination of Ion Atmosphere Effects on the Nucleic Acid Electrostatic Potential and Ligand Association Using AH(+)·C Wobble Formation in Double-Stranded DNA

[Image: see text] The high charge density of nucleic acids and resulting ion atmosphere profoundly influence the conformational landscape of RNA and DNA and their association with small molecules and proteins. Electrostatic theories have been applied to quantitatively model the electrostatic potenti...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Allred, Benjamin E., Gebala, Magdalena, Herschlag, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2017
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5466006/
https://ncbi.nlm.nih.gov/pubmed/28489947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b01830
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