Caffeine Inhibits Human Immunodeficiency Virus Type 1 Transduction of Nondividing Cells

Caffeine is an efficient inhibitor of DNA repair and DNA damage-activated checkpoints. We have shown recently that caffeine inhibits retroviral transduction of dividing cells, most likely by blocking postintegration repair. This effect may be mediated at least in part by a cellular target of caffein...

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Detalhes bibliográficos
Main Authors: Daniel, René, Marusich, Elena, Argyris, Elias, Zhao, Richard Y., Skalka, Anna Marie, Pomerantz, Roger J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546572/
https://ncbi.nlm.nih.gov/pubmed/15681408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2058-2065.2005
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