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A Novel Heterozygous Intragenic Sequence Variant in DLX6 Probably Underlies First Case of Autosomal Dominant Split-Hand/Foot Malformation Type 1

Split-hand and foot malformation (SHFM; MIM 183600) is a rare human genetic limb malformation. It is characterized by missing digital rays in the hands and feet. SHFMs vary in severity from mild abnormalities affecting a single limb to acute malformations involving all 4 limbs. It is inherited, as p...

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Detalhes bibliográficos
Publicado no:Mol Syndromol
Main Authors: Ullah, Asmat, Hammid, Anam, Umair, Muhammad, Ahmad, Wasim
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465671/
https://ncbi.nlm.nih.gov/pubmed/28611547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000453350
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