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Genetic Variability of the Major Histocompatibility Complex Class I Homologue Encoded by Human Cytomegalovirus Leads to Differential Binding to the Inhibitory Receptor ILT2

Human cytomegalovirus carries a gene, UL18, that is homologous to cellular major histocompatibility complex (MHC) class I genes. Like MHC class I molecules, the protein product of the UL18 gene associates with β2-microglobulin, and the stability of this complex depends on peptide loading. UL18 prote...

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Detalhes bibliográficos
Main Authors: Valés-Gómez, Mar, Shiroishi, Mitsunori, Maenaka, Katsumi, Reyburn, Hugh T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC546563/
https://ncbi.nlm.nih.gov/pubmed/15681427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.4.2251-2260.2005
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