Transcranial pulsed ultrasound facilitates brain uptake of laronidase in enzyme replacement therapy for Mucopolysaccharidosis type I disease

BACKGROUND: Mucopolysaccharidosis type I (MPS I) is a debilitating hereditary disease characterized by alpha-L-iduronidase (IDUA) deficiency and consequent inability to degrade glycosaminoglycans. The pathological accumulation of glycosaminoglycans systemically results in severe mental retardation a...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:Orphanet J Rare Dis
Main Authors: Hsu, Yu-Hone, Liu, Ren-Shyan, Lin, Win-Li, Yuh, Yeong-Seng, Lin, Shuan-Pei, Wong, Tai-Tong
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2017
Ábhair:
Research
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465581/
https://ncbi.nlm.nih.gov/pubmed/28595620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-017-0649-6
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla