Development of an objective gene expression panel as an alternative to self-reported symptom scores in human influenza challenge trials

BACKGROUND: Influenza challenge trials are important for vaccine efficacy testing. Currently, disease severity is determined by self-reported scores to a list of symptoms which can be highly subjective. A more objective measure would allow for improved data analysis. METHODS: Twenty-one volunteers p...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Muller, Julius, Parizotto, Eneida, Antrobus, Richard, Francis, James, Bunce, Campbell, Stranks, Amanda, Nichols, Marshall, McClain, Micah, Hill, Adrian V. S., Ramasamy, Adaikalavan, Gilbert, Sarah C.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465537/
https://ncbi.nlm.nih.gov/pubmed/28595644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1235-3
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