Modeling and high-throughput experimental data uncover the mechanisms underlying Fshb gene sensitivity to gonadotropin-releasing hormone pulse frequency

Neuroendocrine control of reproduction by brain-secreted pulses of gonadotropin-releasing hormone (GnRH) represents a longstanding puzzle about extracellular signal decoding mechanisms. GnRH regulates the pituitary gonadotropin's follicle-stimulating hormone (FSH) and luteinizing hormone (LH),...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Stern, Estee, Ruf-Zamojski, Frederique, Zalepa-King, Lisa, Pincas, Hanna, Choi, Soon Gang, Peskin, Charles S., Hayot, Fernand, Turgeon, Judith L., Sealfon, Stuart C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2017
Ämnen:
Gene Regulation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465502/
https://ncbi.nlm.nih.gov/pubmed/28385888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.783886
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