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Two glycosaminoglycan-binding domains of the mouse cytomegalovirus-encoded chemokine MCK-2 are critical for oligomerization of the full-length protein

Chemokines are essential for antimicrobial host defenses and tissue repair. Herpesviruses and poxviruses also encode chemokines, copied from their hosts and repurposed for multiple functions, including immune evasion. The CC chemokine MCK-2 encoded by mouse CMV (MCMV) has an atypical structure consi...

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Vydáno v:J Biol Chem
Hlavní autoři: Pontejo, Sergio M., Murphy, Philip M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465486/
https://ncbi.nlm.nih.gov/pubmed/28432120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.785121
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