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Effect of type 2 diabetes mellitus on the pharmacokinetics and transplacental transfer of nifedipine in hypertensive pregnant women

AIMS: Diabetes mellitus can inhibit cytochrome P450 3A4, an enzyme responsible for the metabolism of nifedipine, used for the treatment of hypertension in pregnant women. We aimed to assess the effect of type 2 diabetes mellitus (T2DM) on the pharmacokinetics, placental transfer and distribution of...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Br J Clin Pharmacol
मुख्य लेखकों: Filgueira, Gabriela Campos de Oliveira, Filgueira, Osmany Alberto Silva, Carvalho, Daniela Miarelli, Marques, Maria Paula, Moisés, Elaine Christine Dantas, Duarte, Geraldo, Lanchote, Vera Lucia, Cavalli, Ricardo Carvalho
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: John Wiley and Sons Inc. 2017
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465346/
https://ncbi.nlm.nih.gov/pubmed/28042936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13226
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