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Effect of type 2 diabetes mellitus on the pharmacokinetics and transplacental transfer of nifedipine in hypertensive pregnant women
AIMS: Diabetes mellitus can inhibit cytochrome P450 3A4, an enzyme responsible for the metabolism of nifedipine, used for the treatment of hypertension in pregnant women. We aimed to assess the effect of type 2 diabetes mellitus (T2DM) on the pharmacokinetics, placental transfer and distribution of...
में बचाया:
में प्रकाशित: | Br J Clin Pharmacol |
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मुख्य लेखकों: | , , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
John Wiley and Sons Inc.
2017
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5465346/ https://ncbi.nlm.nih.gov/pubmed/28042936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13226 |
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