Pretreatment with Sodium Phenylbutyrate Alleviates Cerebral Ischemia/Reperfusion Injury by Upregulating DJ-1 Protein

Oxidative stress and mitochondrial dysfunction play critical roles in ischemia/reperfusion (I/R) injury. DJ-1 is an endogenous antioxidant that attenuates oxidative stress and maintains mitochondrial function, likely acting as a protector of I/R injury. In the present study, we explored the protecti...

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Bibliographic Details
Published in:Front Neurol
Main Authors: Yang, Rui-Xin, Lei, Jie, Wang, Bo-Dong, Feng, Da-Yun, Huang, Lu, Li, Yu-Qian, Li, Tao, Zhu, Gang, Li, Chen, Lu, Fang-Fang, Nie, Tie-Jian, Gao, Guo-Dong, Gao, Li
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465296/
https://ncbi.nlm.nih.gov/pubmed/28649223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2017.00256
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