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Redirected Primary Human Chimeric Antigen Receptor Natural Killer Cells As an “Off-the-Shelf Immunotherapy” for Improvement in Cancer Treatment

Primary human natural killer (NK) cells recognize and subsequently eliminate virus infected cells, tumor cells, or other aberrant cells. However, cancer cells are able to develop tumor immune escape mechanisms to undermine this immune control. To overcome this obstacle, NK cells can be genetically m...

Ausführliche Beschreibung

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Veröffentlicht in:Front Immunol
Hauptverfasser: Oberschmidt, Olaf, Kloess, Stephan, Koehl, Ulrike
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465249/
https://ncbi.nlm.nih.gov/pubmed/28649246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00654
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