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Histones H3 and H4 require their relevant amino-tails for efficient nuclear import and replication-coupled chromatin assembly in vivo

Concomitant chromatin assembly and DNA duplication is essential for cell survival and genome integrity, and requires newly synthesized histones. Although the N-terminal domains of newly synthesized H3 and H4 present critical functions, their requirement for replication-coupled chromatin assembly is...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ejlassi, Aïda, Menil-Philippot, Vanessa, Galvani, Angélique, Thiriet, Christophe
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465201/
https://ncbi.nlm.nih.gov/pubmed/28596587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03218-6
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