Inhibiting STAT3 signaling is involved in the anti-melanoma effects of a herbal formula comprising Sophorae Flos and Lonicerae Japonicae Flos

A herbal formula (SL) comprising Sophorae Flos and Lonicerae Japonicae Flos was traditionally used to treat melanoma. Constitutively active signal transducer and activator of transcription 3 (STAT3) has been proposed as a therapeutic target in melanoma. Here we investigated whether an ethanolic extr...

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Udgivet i:Sci Rep
Main Authors: Li, Ting, Fu, Xiuqiong, Tse, Anfernee Kai-Wing, Guo, Hui, Lee, Kin Wah, Liu, Bin, Su, Tao, Wang, Xueyu, Yu, Zhiling
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465088/
https://ncbi.nlm.nih.gov/pubmed/28596565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03351-2
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