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The miR-125a/HK2 axis regulates cancer cell energy metabolism reprogramming in hepatocellular carcinoma

The Warburg effect is a metabolic hallmark of cancer. Tumor cells rapidly adjust their energy source to glycolysis in order to efficiently proliferate in a hypoxic environment, but the mechanism underlying this switch remains incompletely understood. Here, we show that hypoxia potently induces the d...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Jin, Fangfang, Wang, Yanbo, Zhu, Yanan, Li, Shan, Liu, Ying, Chen, Cheng, Wang, Xiaohua, Zen, Ke, Li, Limin
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465066/
https://ncbi.nlm.nih.gov/pubmed/28596599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03407-3
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