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pH-dependent structural modulation is conserved in the human small heat shock protein HSBP1

The holdase activity and oligomeric propensity of human small heat shock proteins (sHSPs) are regulated by environmental factors. However, atomic-level details are lacking for the mechanisms by which stressors alter sHSP responses. We previously demonstrated that regulation of HSPB5 is mediated by a...

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Detalhes bibliográficos
Publicado no:Cell Stress Chaperones
Main Authors: Clouser, Amanda F., Klevit, Rachel E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5465033/
https://ncbi.nlm.nih.gov/pubmed/28332148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12192-017-0783-z
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