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Melatonin exerts anti-oral cancer effect via suppressing LSD1 in patient-derived tumor xenograft models
Aberrant activation of histone lysine-specific demethylase (LSD1) increases tumorigenicity; hence, LSD1 is considered a therapeutic target for various human cancers. Although melatonin, an endogenously produced molecule, may defend against various cancers, the precise mechanism involved in its anti-...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5464909/ https://ncbi.nlm.nih.gov/pubmed/28422711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16808 |
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