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Microrna-217 modulates human skin fibroblast senescence by directly targeting DNA methyltransferase 1

DNA methyltransferase 1 (DNMT1) is a major epigenetic regulator associated with many biological processes. However, the roles and mechanisms of DNMT1 in skin aging are incompletely understood. Here we explored the role of DNMT1 in human skin fibroblasts senescence and its related regulatory mechanis...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Wang, Ben, Du, Rui, Xiao, Xiao, Deng, Zhi-Li, Jian, Dan, Xie, Hong-Fu, Li, Ji
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464883/
https://ncbi.nlm.nih.gov/pubmed/28380423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16509
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