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Activity-induced spontaneous spikes in GABAergic neurons suppress seizure discharges: an implication of computational modeling

BACKGROUND: Epilepsy, a prevalent neurological disorder, appears self-termination. The endogenous mechanism for seizure self-termination remains to be addressed in order to develop new strategies for epilepsy treatment. We aim to examine the role of activity-induced spontaneous spikes at GABAergic n...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Lu, Wei, Feng, Jing, Wen, Bo, Wang, Kewei, Wang, Jin-Hui
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464796/
https://ncbi.nlm.nih.gov/pubmed/28427143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15660
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