Activity-induced spontaneous spikes in GABAergic neurons suppress seizure discharges: an implication of computational modeling

BACKGROUND: Epilepsy, a prevalent neurological disorder, appears self-termination. The endogenous mechanism for seizure self-termination remains to be addressed in order to develop new strategies for epilepsy treatment. We aim to examine the role of activity-induced spontaneous spikes at GABAergic n...

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Vydáno v:Oncotarget
Hlavní autoři: Lu, Wei, Feng, Jing, Wen, Bo, Wang, Kewei, Wang, Jin-Hui
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2017
Témata:
Research Paper: Pathology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464796/
https://ncbi.nlm.nih.gov/pubmed/28427143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.15660
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