Regeneration of fat cells from myofibroblasts during wound healing

Although regeneration through the reprogramming of one cell lineage to another occurs in fish and amphibians, it has not been observed in mammals. We discovered in the mouse that during wound healing, adipocytes regenerate from myofibroblasts, a cell type thought to be differentiated and nonadipogen...

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Publicado no:Science
Main Authors: Plikus, Maksim V., Guerrero-Juarez, Christian F., Ito, Mayumi, Li, Yun Rose, Dedhia, Priya H., Zheng, Ying, Shao, Mengle, Gay, Denise L., Ramos, Raul, Hsi, Tsai-Ching, Oh, Ji Won, Wang, Xiaojie, Ramirez, Amanda, Konopelski, Sara E., Elzein, Arijh, Wang, Anne, Supapannachart, Rarinthip June, Lee, Hye-Lim, Lim, Chae Ho, Nace, Arben, Guo, Amy, Treffeisen, Elsa, Andl, Thomas, Ramirez, Ricardo N., Murad, Rabi, Offermanns, Stefan, Metzger, Daniel, Chambon, Pierre, Widgerow, Alan D., Tuan, Tai-Lan, Mortazavi, Ali, Gupta, Rana K., Hamilton, Bruce A., Millar, Sarah E., Seale, Patrick, Pear, Warren S., Lazar, Mitchell A., Cotsarelis, George
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464786/
https://ncbi.nlm.nih.gov/pubmed/28059714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aai8792
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