Effect of Fc-γ Receptor Polymorphism on Rituximab-Mediated B Cell Depletion in ABO-Incompatible Adult Living Donor Liver Transplantation

BACKGROUND: The affinity of IgG Fc receptor (FcγR) for rituximab, an anti-CD20 IgG1, differs based on single-nucleotide polymorphisms (SNPs) in FcγRs. This study aimed to explore the effect of such SNPs on clinical response to rituximab and outcomes in patients of ABO-incompatible (ABOi) living dono...

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Dettagli Bibliografici
Pubblicato in:Transplant Direct
Autori principali: Sakai, Hiroshi, Tanaka, Yuka, Tazawa, Hirofumi, Shimizu, Seiichi, Verma, Sapana, Ohira, Masahiro, Tahara, Hiroyuki, Ide, Kentaro, Ishiyama, Kohei, Kobayashi, Tsuyoshi, Onoe, Takashi, Ohdan, Hideki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Lippincott Williams & Wilkins 2017
Soggetti:
Liver Transplantation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464783/
https://ncbi.nlm.nih.gov/pubmed/28620648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TXD.0000000000000683
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