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MicroRNAs upregulated during HIV infection target peroxisome biogenesis factors: Implications for virus biology, disease mechanisms and neuropathology

HIV-associated neurocognitive disorders (HAND) represent a spectrum neurological syndrome that affects up to 25% of patients with HIV/AIDS. Multiple pathogenic mechanisms contribute to the development of HAND symptoms including chronic neuroinflammation and neurodegeneration. Among the factors linke...

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Publicado en:PLoS Pathog
Autores principales: Xu, Zaikun, Asahchop, Eugene L., Branton, William G., Gelman, Benjamin B., Power, Christopher, Hobman, Tom C.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464672/
https://ncbi.nlm.nih.gov/pubmed/28594894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006360
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