ATP-sensitive potassium (K(ATP)) channel openers diazoxide and nicorandil lower intraocular pressure by activating the Erk1/2 signaling pathway

Elevated intraocular pressure is the most prevalent and only treatable risk factor for glaucoma, a degenerative disease of the optic nerve. While treatment options to slow disease progression are available, all current therapeutic and surgical treatments have unwanted side effects or limited efficac...

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Veröffentlicht in:PLoS One
Hauptverfasser: Roy Chowdhury, Uttio, Bahler, Cindy K., Holman, Bradley H., Fautsch, Michael P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464668/
https://ncbi.nlm.nih.gov/pubmed/28594895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179345
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