High sodium diet converts renal proteoglycans into pro-inflammatory mediators in rats

BACKGROUND: High dietary sodium aggravates renal disease by affecting blood pressure and by its recently shown pro-inflammatory and pro-fibrotic effects. Moreover, pro-inflammatory modification of renal heparan sulfate (HS) can induce tissue remodeling. We aim to investigate if high sodium intake in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hijmans, Ryanne S., Shrestha, Pragyi, Sarpong, Kwaku A., Yazdani, Saleh, el Masri, Rana, de Jong, Wilhelmina H. A., Navis, Gerjan, Vivès, Romain R., van den Born, Jacob
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464595/
https://ncbi.nlm.nih.gov/pubmed/28594849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178940
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