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Rotating night work, lifestyle factors, obesity and promoter methylation in BRCA1 and BRCA2 genes among nurses and midwives

Some recent evidence suggests that environmental and lifestyle factors may modify DNA methylation. We hypothesized that rotating night work and several modifiable factors may be associated with the methylation of the promoter regions within two tumor suppressor and DNA repair genes: BRCA1 and BRCA2....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Peplonska, Beata, Bukowska, Agnieszka, Wieczorek, Edyta, Przybek, Monika, Zienolddiny, Shanbeh, Reszka, Edyta
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464581/
https://ncbi.nlm.nih.gov/pubmed/28594926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178792
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