Spinal column chordoma: prognostic significance of clinical variables and T (brachyury) gene SNP rs2305089 for local recurrence and overall survival

BACKGROUND. Chordomas are rare, locally aggressive bony tumors associated with poor outcomes. Recently, the single nucleotide polymorphism (SNP) rs2305089 in the T (brachyury) gene was strongly associated with sporadic chordoma development, but its clinical utility is undetermined. METHODS. In 333 p...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: Bettegowda, Chetan, Yip, Stephen, Lo, Sheng-Fu Larry, Fisher, Charles G., Boriani, Stefano, Rhines, Laurence D., Wang, Joanna Y., Lazary, Aron, Gambarotti, Marco, Wang, Wei-Lien, Luzzati, Alessandro, Dekutoski, Mark B., Bilsky, Mark H., Chou, Dean, Fehlings, Michael G., McCarthy, Edward F., Quraishi, Nasir A., Reynolds, Jeremy J., Sciubba, Daniel M., Williams, Richard P., Wolinsky, Jean-Paul, Zadnik, Patricia L., Zhang, Ming, Germscheid, Niccole M., Kalampoki, Vasiliki, Varga, Peter Pal, Gokaslan, Ziya L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2017
Soggetti:
Clinical Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464366/
https://ncbi.nlm.nih.gov/pubmed/27663388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now156
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