Immunovirotherapy with measles virus strains in combination with anti–PD-1 antibody blockade enhances antitumor activity in glioblastoma treatment

BACKGROUND. Glioblastoma (GBM) is the most common primary malignant brain tumor and has a dismal prognosis. Measles virus (MV) therapy of GBM is a promising strategy due to preclinical efficacy, excellent clinical safety, and its ability to evoke antitumor pro-inflammatory responses. We hypothesized...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Hardcastle, Jayson, Mills, Lisa, Malo, Courtney S., Jin, Fang, Kurokawa, Cheyne, Geekiyanage, Hirosha, Schroeder, Mark, Sarkaria, Jann, Johnson, Aaron J., Galanis, Evanthia
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464320/
https://ncbi.nlm.nih.gov/pubmed/27663389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now179
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