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Birth pangs: the stressful origins of lymphocytes
Inositol-requiring enzyme 1 (IRE1) is a transmembrane protein that signals from the ER and contributes to the generation of an active spliced form of the transcriptional regulator X-box–binding protein 1 (XBP1). XBP1 is required for the terminal differentiation of B lymphocytes into plasma cells, an...
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC546430/ https://ncbi.nlm.nih.gov/pubmed/15690077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200524238 |
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