Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalization

Insulin-stimulated glucose uptake in adipocytes is mediated by translocation of vesicles containing the glucose transporter GLUT4 from intracellular storage sites to the cell periphery and the subsequent fusion of these vesicles with the plasma membrane, resulting in the externalization of GLUT4. Fu...

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Autori principali: Kanda, Hajime, Tamori, Yoshikazu, Shinoda, Hiroaki, Yoshikawa, Mari, Sakaue, Motoyoshi, Udagawa, Jun, Otani, Hiroki, Tashiro, Fumi, Miyazaki, Jun-ichi, Kasuga, Masato
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2005
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC546422/
https://ncbi.nlm.nih.gov/pubmed/15690082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200522681
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