P14.19 Preclinical and clinical efficacy of entrectinib in primary and metastatic brain tumors harboring NTRK, ROS1, or ALK gene fusions

Targeted therapies that effectively cross the blood-brain barrier to treat primary and metastatic brain tumors represent a critical unmet medical need in neuro-oncology. NTRK, ROS1, and ALK gene fusions are seen in over 40 primary solid tumor histologies, many of which may be complicated by brain me...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Rangaraju, S., Farago, A., Heym, K. M., Ahn, M., Drilon, A., Potts, S., Hornby, Z., Multani, P., Li, G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
POSTER PRESENTATIONS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5464020/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.404
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