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P01.30 In vivo effects of isoform-specific inhibition of TGF-β(3) in glioblastoma

Introduction: Transforming growth factor (TGF)-β has been considered a therapeutic target in glioblastoma since decades. However, despite promising preclinical research data, the efficacy of TGF-β-targeted compounds in in vivo models and in clinical trials has been limited. Most recent approaches us...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Seystahl, K., Burghardt, I., Gramatzki, D., Schneider, H., Papachristodoulou, A., Hasenbach, K., Frei, K., Janicot, M., Roth, P., Weller, M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463653/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox036.106
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