Are interferon-γ release assays useful for diagnosing active tuberculosis in a high-burden setting?

Although interferon-γ release assays (IGRAs) are intended for diagnosing latent tuberculosis (TB), we hypothesised that in a high-burden setting: 1) the magnitude of the response when using IGRAs can distinguish active TB from other diagnoses; 2) IGRAs may aid in the diagnosis of smear-negative TB;...

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Publicat a:Eur Respir J
Autors principals: Ling, D.I., Pai, M., Davids, V., Brunet, L., Lenders, L., Meldau, R., Calligaro, G., Allwood, B., van Zyl-Smit, R., Peter, J., Bateman, E., Dawson, R., Dheda, K.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463537/
https://ncbi.nlm.nih.gov/pubmed/21349910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00181610
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