Evaluation of Attenuated Tumor Antigens and the Implications for Peptide-Based Cancer Vaccine Development

INTRODUCTION: Peptide vaccines offer anti-tumor efficacy with very low toxicity. However, repeat stimulation with an immunogenic peptide leads to activation induced cell death (AICD), decreasing efficacy. We engineered variants of an immunogenic peptide (E39) and tested their ability to induce a rob...

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Publicat a:J Cancer
Autors principals: Berry, JS, Vreeland, TJ, Hale, DF, Jackson, DO, Trappey, AF, Greene, JM, Hardin, MO, Herbert, GS, Clifton, GT, Peoples, GE
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5463441/
https://ncbi.nlm.nih.gov/pubmed/28607601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.16450
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